ד"ר אריה גילאי - קורות חיים.

ARIEH GILAI, B.Sc., M.Sc., Ph.D.   

CURRICULUM VITAE

General 


PERSONAL DETAILS


Date and Place of Birth:    June 16, 1938; Jerusalem, Israel.

Marital Status               :    Married (Ruth), two children (Merav, Dan).

Home Address             :    7 Caspi Street, Jerusalem 93554, Israel

Military Service            :     Israeli Defense Force 1956 - 1962.         

Tel:      +972-2-6731050     Fax:     +972-2-6713086

E-mail: click here

 

Education


1962 - 1964  : G.C.E. "A" Level (General Certificate of Education)

N.W. Polytechnic, London, England.

1964 - 1967  : B.Sc. Degree, Hebrew University of Jerusalem, Israel.

                       Major : Physiology.

1967 - 1969  : M.Sc. Degree, with distinction. Hebrew University,

                       Major : Neurophysiology.

1972             : International course in Muscle Biophysics, Italy.

1970 - 1974  : Ph.D. in Neurophysiology, Hebrew University, Jerusalem.

1974 - 1976  : Postdoctoral fellow in Electrophysiology and Biophysics     

                       with Prof. S. Nakajima, Purdue University, Indiana USA

                  

  PROFESSIONAL POSITIONS


1968 - 1972    : Assistant, Department of  Life Sciences, Hebrew University.

1972 - 1974    : Instructor In Neurophysiology, Hebrew University.

1974 - 1976    : Research Associate in Electrophysiology and Biophysics  

                         Purdue University, Indiana U.S.A.

1976 - 1978    : Assistant Professor, Department of Physiology, Rush

                         Medical College, Chicago, U.S.A.

1977 - 1978    :  Assistant Professor in Neurophysiology, Graduate

                          School, Rush University Medical School, U.S.A.

1978 - 1990     : Director, Department of  Clinical Neurophysiology,

                           Shaare  Zedek Medical Center, Jerusalem, Israel.

1990 – 2003    : Director, Department of Clinical Neurophysiology,

                          "ALYN" Children’s Hospital, Jerusalem, Israel.

2003 -  : Retired at the age of 65. Concluding 40 Years of Scientific & Medical activity.

 

 PROFESSIONAL NOMINATIONS


1987 -             Member of the International Program Committee for the VIIth  International EMG congress. (Sorrento, Italy)/

 

1988 -              Chairman of the International Committee for the  proposition of standardized terminology and criteria for EMG analysis.

 

1988 -              Member of the Organizing Committee for the IIIed

                        Quantitative EMG Congress. (Mainz, Germany)

 

1988 -              Chairman of the Israeli Society of Clinical Neurophysiology

                        (ISCN) (1988 - 1993).

 

1989 -              Convener and Chairman of the IX International Congress of EMG and Clinical Neurophysiology (1992).

 

1989 -              Member of the Scientific Program Committee for the XII

                        International EEG Congress (Vacouver, Canada 1990).

 

1990 -              Member of the Organizing Committee for the IVth Quantitative EMG Congress. (Nicosia, Cyprus)

 

1993 -             Member of the International Program Committee for the Xth  International EMG congress. (Kyoto, Japan 1995)

 

1993 - 1998    President, International Society for Computerized EMG.

 

 

 PROFESSIONAL EXPERIENCE


Teaching Experience


 

1969 – 1974    Instructor in Neurophysiology and Comparative Physiology, Hebrew University, Jerusalem, Israel.

1976 - 1978     Teaching Human Neurophysiology at Rush Medical College, U.S.A.

1977 - 1978     Developing, implementing and evaluating curriculum in Muscle Physiology for Ph.D. students at the graduate school, Rush University, Chicago, U.S.A.

1979 - 1981     Teaching Neurophysiology at the Negev University Medical School.

1979 - 1983     Developing curriculum and teaching Human  Physiology in the College of Nursing, Shaare Zedek Medical Center.

1980 - 1990     Scientific instructor of resident physicians and  B.Sc.  (Eng.) students in applied Electrophysiology.

1988 - 1994     Developing curriculum and teaching Clinical  Electrophysiology, Tel Aviv University, School of Medicine (Continuous Education).

 

 PROFESSIONAL EXPERIENCE


 RESEARCH EXPERIENCE


General       Basic and applied investigation of neuromuscular function and establishing electrophysiological criteria of nerve and muscle dysfunction for clinical diagnosis.
 

Specific         Studies of the Biophysical and Neurophysiological

                        properties of Neuromuscular systems in the following subjects:

 

                                             1.      Electrophysiology of Muscle. - The passive and active electrical properties of the surface and T-system membranes.

                                             2.      Neurophysiology. - Evoked Potentials of peripheral and central nervous system in demyelinating disorders.

                                             3.      Electromyography (EMG). - Quantitative EMG and single fiber EMG in myopathic and neurogenic disorders.

                                             4.      Pharmacology. - Evaluation of drug efficacy and site of action.

                                             5.      Mechanics of Muscle. - Isotonic and isometric properties of skeletal muscles.

                                             6.      Electron microscopy. - The ultrastructure of skeletal muscles and synaptic region.

                                             7.      Applied Research. - Design and development of computerized medical equipment for routine diagnosis and therapeutic use.

 

RESEARCH GRANTS.


 

1974                Funding agency: Muscular Dystrophy of America. Studies in E-C coupling in striated muscle.

 

1975                Funding agency: Grass Foundation. Physiological polyneural inhibitory innervation.

 

1976                Funding agency: BRSG Chicago. Intracellular Myography – A diagnostic tool for myopathies.

 

1977                Funding agency: Chicago Heart. Excitation Contraction in heart  muscles.

 

1980                Funding agency: Dysautonomia Foundation. Reversal of sympathectomy by nerve growth factor.

 

1983                     Funding agency: Earl Mandell Research Foundation. Quantification of EMG Interference Pattern in neurogenic and myopathic disorders.

 

PROFESSIONAL EXPERIENCE


ROUTINE CLINICAL  NEUROPHYSIOLOGY


1974 - 2003            Performing and evaluating the following clinical tests:

 

                                                                      1.                    Nerve Conduction Studies (NCS)

 

                                                                      2.                    Somatosensory Evoked Potentials (SEP)

 

                                                                      3.                    Electromyography (EMG)

 

                                                                      4.                    Brain stem Auditory Evoked Potentials (BAEP)

 

                                                                      5.                    Visual Evoked Potentials (VEP)

 

                                                                      6.                    Electroretinography (ERG)

 

LIST  OF  PUBLICATIONS   רשימת פרסומים



לקריאת תקצירים של חלק מהמאמרים של ד"ר גילאי, נא עיין ב - רשימה הבאה


1. GILAI, A.N. and PARNAS, I. (1970). NEUROMUSCULAR PHYSIOLOGY OF THE CLOSER MUSCLES IN THE  PEDIPULP OF THE SCORPION LEIURUS QUINQUESTRIATUS. J. EXP. BIOL. 52, 325.
 

2. GILAI, ARIEH. (1970). NEUROMUSCULAR PHYSIOLOGY OF TUBULAR MUSCLE FIBERS. M.Sc. THESIS, HEBREW UNIVERSITY. (IN HEBREW).

 

3. GILAI, A.N. and PARNAS, I. (1972) ELECTROMECHANICAL COUPLING IN TUBULAR MUSCLE FIBERS. ISRAEL JOURNAL OF MEDICAL SCIENCE.   8, 4. (ABSTRACT).

 

4. GILAI, A.N. and PARNAS, I. (1972) ELECTROMECHANICAL COUPLING IN TUBULAR FIBER. I. THE ORGANIZATION OF TUBULAR MUSCLE FIBER IN THE SCORPION LEIURUS QUINQUESTRIATUS.   J. CELL BIOL.  52, 626

 

5. GILAI, ARIEH. (1974) CORRELATED ULTRASTACTURAL AND BIOPHYSICAL STUDIES ON TUBULAR MUSCLE FIBERS. Ph. D. THESIS,  HEBREW UNIVERSITY (IN ENGLISH).

 

6. GILAI, A.N. (1975) ALTERNATING CURRENT ANALYSIS IN SCORPION MUSCLE FIBERS. BIOPHYS. J. 15, 256

 

7. GILAI, A.N. and NAKAJIMA, S. (1976) DYE ABSORPTION CHANGES DURING EXCITATION OF SINGLE MUSCLE FIBERS. BIOPHYS. J. 16, 153.

 

8. GILAI, A.N. (1976) ELECTROMECHANICAL COUPLING IN TUBULAR FIBER. II. THE RESISTANCE AND CAPACITANCE OF ONE TRANSERVERSE TUBULAR. J. GEN. PHYSIOL. 67, 290

 

9. NAKAJIMA, S. , A. GILAI and DINGEMAN (1976) A SIMPLE CIRCUIT FOR           AUTOMATIC ANALYSIS OF OSCILLOSCOPE BEAM: AN PPLICATION TO RECORDING DYE ABSORPTION CHANGES.  PFLUGERS ARCH. GES. PHYSIOL. 362, 258.

 

10. GILAI, A.N. and KIRSCH, G. (1976) LATENCY RELAXATION IS NOT RELATED TO Ca++ RELEASE PER SE. BIOPHYS. J. 16,123

 

11. GILAI, A.N. (1977) ON THE RELATION BETWEEN LATENCY RELAXATION AND TWITCH RELAXATION IN SKELETAL MUSCLE. FED. PROC. 36, 584

 

12. NAKAJINA, S. and GILAI, A.N. (1977). RECORDING OF ACTION POTENTIAL  FROM SINGLE MUSCLE FIBERS USING POTENTIAL SENSITIVE DYES.  J. GEN. PHYSIOL.  70, (6), 29.

 

13. GILAI, A.N. and EISENBERG, B.R. (1977). STRUCTURAL CHANGES IN           STIMULATED MUSCLE FIBERS.  J.CELL BIOL. 75, 147.

 

14. GILAI, A.N. and MATHIAS, R.T. (1977). SUPPRESSION OF LATENCY RELAXATION IN SKELETAL MUSCLE: EVIDENCE FOR A LINK TO AN EVENT PRECEDING CALCIUM RELEASE. J. GEN. PHYSIOL.  70, 18.

 

15. GILAI, A.N. and KIRSCH G. (1978). LATENCY RELAXATION IN SINGLE MUSCLE FIBERS. J. PHYSIOL.  (LONDON).  282, 197.

 

16. NAKAJIMA, S. and GILAI, A.N. (1978). ABSORPTION CHANGES IN SINGLE MUSCLE FIBERS STAINED WITH MEROCYANINE 540, ww375, OR NK 2367. SIX INTERNATIONAL BIOPHYSICS CONGRESS.   (ABSTRACT).

 

17. FISHER, M.A, GILAI, A.N. and GRACIA, H. (1978). H - REFLEX IN FLEXOR AND EXTENSOR MUSCLES.  NEUROLOGY. Vol. 28, 338.

 

18. NAKAJIMA, S. and GILAI, A.N. (1978). DYE ABSORPTION IN SINGLE MUSCLE FIBERS.  BIOPHYS.  J.  18.

 

19. EISENBERG, B., EISENBERG, R. and GILAI, A.N. (1978) STRUCTURAL CHANGES IN THE T-SR JUNCTION IN ACTIVELY CONTRACTING SKELETAL MUSCLE.  J.  GEN.  PHYSIOL. Vol.  73, 15.

 

20. GRACIA, H., FISHER, M.A., and GILAI, A.N. (1979). H-REFLEX ANALYSIS OF SEGMENTAL REFLEX EXCITABILITY IN FLEXOR AND EXTENSOR MUSCLES. NEUROLOGY. Vol. 29, 984.

 

21. EISENBERG, B., MATHIAS, R.T. and GILAI, A.N. (1979). INTRACELLULAR LOCALIZATION OF MARKERS WITHIN INJECTED OR CUT FROG MUSCLE FIBERS.  Am.  J.  PHYSIOL.  273, 50.

 

22. EISENBERG, B. and GILAI, A.N. (1979). STRUCTURAL CHANGES IN SINGL MUSCLE FIBER. J. PHYSIOL.  74, 1.

 

23. NAKAJIMA, S. and GILAI, A.N. (1980). ACTION POTENTIAL OF ISOLATED SINGLE MUSCLE FIBERS MEASURED BY POTENTIAL SENSITIVE DYES.  J. GEN. PHYSIOL. Vol.  76, 729.

 

24. GILAI, A.N. (1980). PHYSIOLOGICAL ASPECTS OF MUSCULAR FATIGUE. ISRAEL J. MED. SCI.   48, 11.

 

25. NAKAJIMA, S., and GILAI, A.N. (1980). RADIAL PROPAGATION OF MUSCLE ACTION POTENTIAL ALONG THE TUBULAR SYSTEM EXAMINED BY POTENTIAL SENSITIVE DYES.  J. GEN. PHYSIOL.  76, 751.

 

26. NAKAJIMA, S., and GILAI, A.N. (1980). THE USE OF MEROCYANINE DYES AS POTENTIAL PROBES IN SKELETAL MUSCLES. IN: THE REGULATION OF MUSCLE CONTRACTION: THE EXCITATION - CONTRUCTION COUPLING. ED. A. GRINNEL. ACADEMIC PRESS.

 

27. BEN-HUR, N., GILAI, A.N., and GOLAN, J. (1980). ELECTROMYOGRAPHY AND BIOFEED BACK TECHNIQUE IN RECONSTRUCTION OF ANAL SPHINCTSR BY GRACILIS MUSCLE TRANSFER.  BRITISH J. PLASTIC SURGERY.  33, 152.       

 

28. POMERANZ, A., DRUKKER, A., MOR, Y., and GILAI, A.N. (1981). ELECTROPHYSIOLOGICAL ASSESSMENT OF CHILDREN WITH CHRONIC RENAL FAILURE.  4th CONGRESS OF CLINICAL PEDIATRICS.  (ABSTRACT).

 

30. GILAI, A.N., and WIENER, F. (1983). AN ELECTROPHYSIOLGICAL MEASURMENT AND REPORTING SYSTEM.  ELECTROENCEPHAL. CLIN.  NEUROPHYSIOL. 57, 3.

 

31. AMIR N, SHALEV RS, BERMAN M, GILAI A, MOR J. (1984). STEROID-RESPONSIVE POSTINFECTIOUS SENSORINEURAL HEARING LOSS. ANN NEUROL. 1984 FEB; 15(2): 212-3.

 

32. WIENER, F., AND GILAI, A.N. (1984). A MICROCOMPUTER BASED CLINICAL INFORMATION SYSTEM FOR A NEUROLOGY INSTITUTE. COMPUTE. AND MEDICINE  2:6, 41.           

 

33. GILAI, A.N., AND ROTH, V.G. (1984). QUANTITATIVE ELECTROMYOGRAPHY OF THE MULTIFIDUS MUSCLES IN LOW BACK PAIN. PROC. IX INT.CONGR. PHYS.   MED.  REHABIL., 32.

 

34. GILAI, A.N., AND KOIFMAN, B. (1985). MICROCOMPUTER SYSTEM FOR ANALYSIS OF ELECTROPHYSIOLOGICAL TESTS. ISRAEL  J. FOR INFORMATION ON EDP.   32, 10.             

 

35. GILAI, A.N., BALKIN, J., AND ZION, M. (1985). EFFECTS OF PROPRANOLOL ON FATIGUE OF SKELETAL MUSCLE. AM. COLL. OF CARDIOLOGY.

 

36. BRAVERMAN D, PATZ J, GILAI A. (1985). [PERIPHERAL AND CENTRAL NEUROLOGICAL SYNDROME IN CHRONIC IDIOPATHIC INTESTINAL PSEUDO-OBSTRUCTION] HAREFUAH. NOV 15; 109(10): 272-4.

 

37. RONEN, S., SILVERSTON, B.Z., NAWRATJKY, J., BERSON, D. AND GILAI, A.N. (1985). EVALUATION OF PATTERN SHIFT VEP AS A PREDICTOR OF AMBLYOPIC TREATMENT OUTCOME. INTERNATIONAL SYMPOSIUM ON STRABISMUS AND AMBLYOPIA  (ABSTRACT).

 

38. GILAI, A.N., (1985). CONTINOUS EMG INTERFERENCE PATTERN ANALYSIS  (CIP) IN MUSCLE FATIGUE AND NEUROMUSCULAR DISORDERS. 11TH INTERNATIONAL CONGRESS OF EEG AND CLINICAL NEUROPHYSIOLOGY

        

39. GILAI, A.N., HADAS-HALPERIN, I. AND ROTH, V.G. (1985). CONTINUOUS EMG INTERFERENCE PATTERN ANALYSIS AND COMPUTERIZED TOMOGRAPHY OF MUSCLES. ELECTROENCEPH. CLIN. NEUROPHYSIOL. 61: S57.

 

40. STEINBERG, A. AND GILAI, A.N., (1985). TRAINING PROGRAM FOR  ELECTRO -   PHYSIOLOGICAL TECHNICIANS IN ISRAEL. 11TH INTERNATIONAL CONGRESS OF EEG AND CLINICAL NEUROPHYSIOLOGY (ABSTRACT).

 

41. FABER, J., FICH, A., STEINBERG, A., RACHMILEVITZ, D., AND GILAI, A.N. (1986). FAMILIAL INTESTINAL PSEUDOOBSTRACTION DOMINATED BY A FROGRESSIVE NEUROLOGICAL DISEASE IN YOUNG AGE. GASTROENTEROLOGY

       

42. GILAI, A.N. (1986). EMG INTERFERENCE PATTERN ANALYSIS IN DISORDERS OF LOWER MOTOR NEURON, SCHWAN AND MUSCLE CELLS.   MUSCLE AND NERVE 9: 245

 

43. DAVIDAI G, ZAKARIA T, GOLDSTEIN R, GILAI A, FREIER S. (1986). HYPOVITAMINOSIS E INDUCED NEUROPATHY IN EXOCRINE PANCREATIC FAILURE. ARCH DIS CHILD. SEP; 61(9): 901-3.

 

44. GILAI, A.N. AND BALKIN, J. (1986). EMG INTERFERENCE PATTERN ANALYSIS OF MUSCLE FATIGUE DURING SUSTAINED ISOMETRIC CONTRACTION.  MUSCLE AND NERVE. 9: 250

 

44. STEINER I, STEINBERG A, ARGOV Z, FABER J, FICH A, GILAI A. (1987). FAMILIAL PROGRESSIVE NEURONAL DISEASE AND CHRONIC IDIOPATHIC INTESTINAL PSEUDO-OBSTRUCTION. NEUROLOGY. JUN; 37(6): 1046-50.

 

45. GILAI, A.N., (1987). QUANTITATIVE ANALYSIS OF EMG INTERFERENCE PATTERN ACTIVITY. ELECTROENCEPH. CLIN. NEUROPHYSIOL. 66: 39

 

46. NESHER G, ROSENBERG P, SHORER Z, GILAI A, SOLOMONOVICH A, SONNENBLICK M. (1987). INVOLVEMENT OF THE PERIPHERAL NERVOUS SYSTEM IN TEMPORAL ARTERITIS-POLYMYALGIA RHEUMATICA. REPORT OF 3 CASES AND REVIEW OF THE LITERATURE. J RHEUMATOL. APR; 14(2): 358-60.

 

47. GILAI, A.N. (1987). CONTINUOUS EMG INTERFERENCE PATTERN ANALYSIS.  ELECTROMYOGR. CLIN. NEUROPHYSIOL 27: 339-348.

 

48. FABER J, FICH A, STEINBERG A, STEINER I, GRANOT E, ALON I, RACHMILEVITZ D,FREIER S, GILAI A. (1987). FAMILIAL INTESTINAL PSEUDOOBSTRUCTION DOMINATED BY A PROGRESSIVE NEUROLOGICAL DISEASE AT A YOUNG AGE. GASTROENTEROLOGY. MAR; 92(3): 786-90.

 

49. GILAI, A.N. (1987). CHANGES IN ACTIVITY DURING CONTRACTION OF MOTOR UNITS  AND SINGLE MUSCLE FIBERS. IN: W.A. NIX (ED.), DIFFERENT MOTOR UNIT. GUTENBERG UNIVERSITY, MAINZ, 3-4

 

50. GADOTH, N., BECHAR, M., SEGEV, J., KUSHNIR, M. AND GILAI, A.N. (1988). ABNORMAL  ORBICULARIS OCULI REFLEX RESPONSE IN SLEEP APNEA SECONDARY  TO ACROMEGALY. ISRAEL J. MED. SCIENCES,  24: 96-100

 

51. GILAI, A.N. (1989). ANALYSIS OF TURNS AND AMPLITUDE IN EMG. CLINICAL NEUROPHYSIOLOGY UPDATE 2: 143-160.

 

52. SINGER R, JOSEPH K, GILAI AN, MEYER S. (1991). NONTRAUMATIC, ACUTE NEONATAL PARAPLEGIA. J PEDIATR ORTHOP. 1991 SEP-OCT; 11(5): 588-93.

 

53. KAUFMAN, E., MEYER, S., WOLNERMAN, J.S. AND GILAI, A.N. (1991). TRANSIENT SUPPRESSION OF INVOLUNTARY MOVEMENT IN CEREBRAL PALSY  PATIENTS DURING DENTAL TREATMENT. ANESTH. PROG. 38: 200-205.

 

54. STRICH, D., GOLDSHTEIN, R., LEVI, E., GILAI, A.N. AND FREIER, S. (1991)  HYPOLIPOPROTEINEMIA WITH A VARIANT NOT PREVIOUSLY REPORTED. HAREFUA 121: 285 – 290.

 

55. MAKIN, M., MEYER, S. AND GILAI, A.N. (1992). PERTHES DISEASE AND POSTERIOR  LUMBOSACRAL UNION. J. PEDIATRIC ORTHOPEDICS, 12: 607-909.

 

56. GILAI, A.N., (1994). EMG INTERFERENCE PATTERN ANALYSIS IN INFANTS: A 10-YEAR FOLOW-UP EXPERIENCE. ELECTROENCEPH. CLIN. NEUROPHYSIOL. 91: 129P

 

57. GILAI, A.N., (1995). "BURST EMG" ANALYSIS. ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY 95: 76P

 

58. FELDBRIN Z, GILAI A.N, EZRA E, KHERMOSH O, KRAMER U, WIENTROUB S. (1995). MUSCLE IMBALANCE IN THE AETIOLOGY OF IDIOPATHIC CLUB FOOT. AN ELECTROMYOGRAPHIC STUDY. J BONE JOINT SURG BR. JUL; 77(4): 596-601.

 

59. VAISMAN N, TABACHNIK E, SHAHAR E, GILAI A.N. (1996). IMPAIRED BRAINSTEM AUDITORY EVOKED POTENTIALS IN PATIENTS WITH CYSTIC FIBROSIS. DEV MED CHILD NEUROL. JAN; 38(1): 59-64.

 

60. FLUMAN Y, LIRAM N, GILAI A.N. (1997). SPINAL MANIPULATION RESULTS IN IMMEDIATE H-REFLEX CHANGES IN PATIENTS WITH UNILATERAL DISC HERNIATION. EUR SPINE J.; 6(6): 398-401

 

61.  SHUPER A, GILAI A.N, STARK B, ZEEVI O, COHEN I.J, ZAIZOV R. (1998). MYOPATHIC CHANGES AS A PARANEOPLASTIC SIGN IN CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA. CLIN PEDIATR (PHILA). SEP; 37(9): 565-7.

 

62. BRAYDA-BRUNO, M., FLUMAN, Y., GIALI, A.N., MEYER. S. (1998). STRATEGIES IN IDIOPATHIC LEFT THORACIC SCOLIOSIS.  IN THE BOOK: SPINE – STATE OF THE ART REVIEWS. VOL. 12, NO. 1, 85 - 90

 

63. STALBERG E, FALCK B, GILAI A.N, JABRE J, SONOO M, TODNEM K. (1999). STANDARDS FOR QUANTIFICATION OF EMG AND NEUROGRAPHY. THE INTERNATIONAL FEDERATION OF CLINICAL NEUROPHYSIOLOGY. ELECTROENCEPHALOGR CLIN NEUROPHYSIOL SUPPL.; 52:213-20. (A CHAPTER IN A BOOK.)

 

64. EZRA E, HAYEK S, GILAI AN, KHERMOSH O, WIENTROUB S. (2000). TIBIALIS ANTERIOR TENDON TRANSFER FOR RESIDUAL DYNAMIC SUPINATION DEFORMITY IN TREATED CLUB FEET. J PEDIATR ORTHOP B. JUN; 9(3): 207-11.

 

65. EIDLITZ-MARKUS T, GILAI A.N, MIMOUNI M, SHUPER A. (2001).  RECURRENT FACIAL NERVE PALSY IN PAEDIATRIC PATIENTS. EUR J PEDIATR. 2001 NOV; 160(11): 659-63.